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testosterone therapy – Mayo Clinic

July 24th, 2015 by rosariogates No comments »

Testosterone therapy: Potential benefits and risks as you age

Considering testosterone therapy to help you feel younger and more vigorous as you age? Know the risks before you make your decision.

The promise of testosterone therapy may seem enticing, but there are a lot of misconceptions about what the treatment can and can’t do for you. As you get older, testosterone therapy may sound like the ultimate anti-aging formula.

Yet the health benefits of testosterone therapy for age-related decline in testosterone aren’t as clear as they may seem. Find out what’s known and not known about testosterone therapy for normal aging.

Testosterone is a hormone produced primarily in the testicles. Testosterone helps maintain men’s:

Testosterone levels generally peak during adolescence and early adulthood. As you get older, your testosterone level gradually declines typically about 1 percent a year after age 30 or 40. It is important to determine in older men if a low testosterone level is simply due to the decline of normal aging or if it is due to a disease (hypogonadism).

Hypogonadism is a disease in which the body is unable to produce normal amounts of testosterone due to a problem with the testicles or with the pituitary gland that controls the testicles. Testosterone replacement therapy can improve the signs and symptoms of low testosterone in these men. Doctors may prescribe testosterone as injections, pellets, patches or gels.

Not necessarily. Men can experience many signs and symptoms as they age. Some may occur as a result of lower testosterone levels and can include:

Some of these signs and symptoms can be caused by various underlying factors, including medication side effects, obstructive sleep apnea, thyroid problems, diabetes and depression. It’s also possible that these conditions may be the cause of low testosterone levels, and treatment of these problems may cause testosterone levels to rise. A blood test is the only way to diagnose a low testosterone level.

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testosterone therapy – Mayo Clinic

Nismat / Home

July 24th, 2015 by cpclubpenguincp No comments »

Welcome to the Nicholas Institute of Sports Medicine and Athletic Trauma (NISMAT), a world-renowned research, teaching, and treatment center. Established at Lenox Hill Hospital in 1973, NISMAT was the worlds first hospital-based facility committed solely to the study of sports medicine, and has since played a key role in advancing the field, as well as redefining its focus. Once perceived as a discipline concerned only with repairing athletes’ traumatic injuries, sports medicine is now recognized as a science that expands the understanding of the relationship between exercise and fitness at all levels, across every age group. Whether youre a medical practitioner or a patient, a professional athlete–or a weekend one, an occasional jogger or a marathon runner, woman or man,…

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Welcome to the Nicholas Institute of Sports Medicine and Athletic Trauma (NISMAT), a world-renowned research, teaching, and treatment center. Established at Lenox Hill Hospital in 1973, NISMAT was the worlds first hospital-based facility committed solely to the study of sports medicine, and has since played a key role in advancing the field, as well as redefining its focus. Once perceived as a discipline concerned only with repairing athletes’ traumatic injuries, sports medicine is now recognized as a science that expands the understanding of the relationship between exercise and fitness at all levels, across every age group. Whether youre a medical practitioner or a patient, a professional athlete–or a weekend one, an occasional jogger or a marathon runner, woman or man, adolescent or octogenarian, NISMAT brings you the most comprehensive and current medical information and references available. Here, youll learn about injury treatment and prevention. Training tips and exercise programs. Physical therapy, sports physiology, nutrition, and so much more. Welcome to NISMAT.

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Emerging interactions between skin stem cells and their …

July 23rd, 2015 by Nikol_snide No comments »

Hair follicle lineage and niche signals regulate hair follicle stem cells. (a) HFSCs can exist in two states. Quiescent bulge stem cells (Bu-SCs) are located in the outer layer of this niche and contribute to the generation of the outer root sheath. Primed stem cells reside in the hair germ, sandwiched between the bulge and a specialized dermal cluster known as the dermal papilla. They are responsible for generating the transit amplifying cell (TAC) matrix, which then gives rise to the hair shaft and its inner root sheath (IRS) channel. Although matrix and IRS are destroyed during catagen, many of the outer root sheath (ORS) cells are spared and generate a new bulge right next to the original one at the end of catagen. The upper ORS contributes to the outer layer of the new bulge, and the middle ORS contributes to the hair germ. Some of the lower ORS cells become the differentiated inner keratin 6+ (K6+) bulge cells, which provide inhibitory signals to Bu-SCs, raising their activation threshold for the next hair cycle. (b) During telogen, K6+ bulge cells produce BMP6 and FGF-18, dermal fibroblasts (DFs) produce BMP4 and subcutaneous adipocytes express BMP2. Together, these factors maintain Bu-SCs and hair germ in quiescence. At the transition to anagen, BMP2 and BMP4 are downregulated, whereas the expression of activation factors including noggin (NOG), FGF-7, FGF-10 and TGF-2 from dermal papillae and PDGF- from adipocyte precursor cells (APCs) is elevated. This, in turn, stimulates hair germ proliferation, and a new hair cycle is launched. Bu-SCs maintain their quiescent state until TAC matrix is generated and starts producing SHH.

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Stem cell controversy – Wikipedia, the free encyclopedia

July 22nd, 2015 by Fasssdexgfred No comments »

The stem cell controversy is the consideration of the ethics of research involving the development, usage, and destruction of human embryos. Most commonly, this controversy focuses on embryonic stem cells. Not all stem cell research involves the creation, usage and destruction of human embryos. For example, adult stem cells, amniotic stem cells and induced pluripotent stem cells do not involve creating, using or destroying human embryos and thus are minimally, if at all, controversial.

The use of stem cells has been happening for decades. In 1998, scientists discovered how to extract stem cells from human embryos. This discovery led to moral ethics questions concerning research involving embryo cells, such as what restrictions should be made on studies using these types of cells? At what point does one consider life to begin? Is it just to destroy an embryo cell if it has the potential to cure countless numbers of patients? Political leaders are debating how to regulate and fund research studies that involve the techniques used to remove the embryo cells. No clear consensus has emerged. Other recent discoveries may extinguish the need for embryonic stem cells.[1]

Since stem cells have the ability to differentiate into any type of cell, they offer something in the development of medical treatments for a wide range of conditions. Treatments that have been proposed include treatment for physical trauma, degenerative conditions, and genetic diseases (in combination with gene therapy). Yet further treatments using stem cells could potentially be developed thanks to their ability to repair extensive tissue damage.[2]

Great levels of success and potential have been shown from research using adult stem cells. In early 2009, the FDA approved the first human clinical trials using embryonic stem cells. Embryonic stem cells can become all cell types of the body which is called totipotent. Adult stem cells are generally limited to differentiating into different cell types of their tissue of origin. However, some evidence suggests that adult stem cell plasticity may exist, increasing the number of cell types a given adult stem cell can become. In addition, embryonic stem cells are considered more useful for nervous system therapies, because researchers have struggled to identify and isolate neural progenitors from adult tissues[citation needed]. Embryonic stem cells, however, might be rejected by the immune system – a problem which wouldn’t occur if the patient received his or her own stem cells.

Some stem cell researchers are working to develop techniques of isolating stem cells that are as potent as embryonic stem cells, but do not require a human embryo.

Some believe that human skin cells can be coaxed to “de-differentiate” and revert to an embryonic state. Researchers at Harvard University, led by Kevin Eggan, have attempted to transfer the nucleus of a somatic cell into an existing embryonic stem cell, thus creating a new stem cell line.[3] Another study published in August 2006 also indicates that differentiated cells can be reprogrammed to an embryonic-like state by introducing four specific factors, resulting in induced pluripotent stem cells.[4]

Researchers at Advanced Cell Technology, led by Robert Lanza, reported the successful derivation of a stem cell line using a process similar to preimplantation genetic diagnosis, in which a single blastomere is extracted from a blastocyst.[5] At the 2007 meeting of the International Society for Stem Cell Research (ISSCR),[6] Lanza announced that his team had succeeded in producing three new stem cell lines without destroying the parent embryos. “These are the first human embryonic cell lines in existence that didn’t result from the destruction of an embryo.” Lanza is currently in discussions with the National Institutes of Health (NIH) to determine whether the new technique sidesteps U.S. restrictions on federal funding for ES cell research.[7]

Anthony Atala of Wake Forest University says that the fluid surrounding the fetus has been found to contain stem cells that, when utilized correctly, “can be differentiated towards cell types such as fat, bone, muscle, blood vessel, nerve and liver cells”. The extraction of this fluid is not thought to harm the fetus in any way. He hopes “that these cells will provide a valuable resource for tissue repair and for engineered organs as well”.[8]

The status of the human embryo and human embryonic stem cell research is a controversial issue as, with the present state of technology, the creation of a human embryonic stem cell line requires the destruction of a human embryo. Stem cell debates have motivated and reinvigorated the pro-life movement, whose members are concerned with the rights and status of the embryo as an early-aged human life. They believe that embryonic stem cell research instrumentalizes and violates the sanctity of life and is tantamount to murder.[9] The fundamental assertion of those who oppose embryonic stem cell research is the belief that human life is inviolable, combined with the belief that human life begins when a sperm cell fertilizes an egg cell to form a single cell.

A portion of stem cell researchers use embryos that were created but not used in in vitro fertility treatments to derive new stem cell lines. Most of these embryos are to be destroyed, or stored for long periods of time, long past their viable storage life. In the United States alone, there have been estimates of at least 400,000 such embryos.[10] This has led some opponents of abortion, such as Senator Orrin Hatch, to support human embryonic stem cell research.[11] See Also Embryo donation.

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Stem cell controversy – Wikipedia, the free encyclopedia

Endocrinology, Diabetes and Metabolism – CHP

July 21st, 2015 by thorrooferazxcl No comments »

Description of Services

The Division of Pediatric Endocrinology, Diabetes and Metabolism Consultation provides diagnostic and therapeutic services for children with diabetes mellitus, hypoglycemia and disorders of physical growth, sexual maturation, thyroid function, pituitary function, and calcium and phosphorous metabolism.

The Pediatric Endocrine Testing Center provides diagnostic endocrine tests for patients (both children and adults) in areas of endocrinology and carbohydrate, amino acid, and mineral and lipid metabolism. The center addresses growth abnormalities and the range of conditions that can cause them.

The Nutrition Consultation Service provides consultative and follow-up service by a physician and dietitian for children up to 18 years of age with obesity problems and associated disorders.

Referrals are required from primary care physicians or other Childrens Hospital specialty services. These should be accompanied by a written reason for the referral together with related patient records and growth charts. Referrals for patients enrolled in managed care insurance plans also require authorization from the primary care physician and sometimes from the insurance provider. All necessary referral and authorization forms must be received before the patients visit and include separate authorization for each physician, diabetes nurse educator, dietitian, laboratory and X-ray services. For accurate provider numbers or more information, please call the office number listed.

205 Millers Run Road

Contact Information: 412-692-7337

4055 Monroeville Blvd., Building One

Contact Information: 412-692-7337

2599 Wexford Bayne Rd.

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Endocrinology, Diabetes and Metabolism – CHP

New Vitality Ageless Male Testosterone Booster Softgels …

July 20th, 2015 by buycheaffoftsa No comments »

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Lack of Energy May Mean Lack of Testosterone – DrAxe.com

July 20th, 2015 by sylvialkw No comments »

When most of us hear the word testosterone we think of puberty and men in their twenties sowing their oats. We also tend to think of bulky body builders pumped up and maxed out. However testosterone plays many more roles in the health of both men and women than many of us realize.

And low levels of testosterone in both sexes may cause serious negative health consequences.

Whats more is it seems that testosterone levels in both men and women are getting lower at earlier ages. In fact, its estimated that twenty-five percent of men over the age of forty-five have low levels of testosterone, or hypogonadism as its called. Thats about 15 million American men, according to an article in the New York Daily Times.

What exactly is testosterone, you may wonder? Testosterone is the main hormone in the male. Its what we attribute to making men manly and propelling their sex drive. Technically speaking, it is an androgen, a hormone found more in males but also in females. Produced by the testes in men and the ovaries and adrenal glands in women, this anabolic steroid is often used to bulk up muscles and retain protein in the muscles enabling growth.

Testosterone levels in both sexes naturally decline with age; in men the decline begins around age forty and in women this slow decrease begins in the twenties and continues into the forties and menopause.

But testosterones role in both men and womens bodies goes beyond the sex drive and muscles. In fact, low levels of testosterone are now being associated with a number of serious health issues in both sexes.

Low testosterone is associated with increased risk of coronary artery disease (CAD), diabetes, osteoporosis, infertility, and more.

When it comes to testosterone levels, symptoms, and health issues theres some controversy as to which causes which.

For example, in men who are obese its found they have lower levels of testosterone. But its well known that obesity in men changes the male hormones into female ones. So is it the obesity causing the lower testosterone levels or the lower testosterone levels contributing to the obesity problem? A classic chicken or the egg question.

Medical professionals speculate that low testosterone could be anindicator of a general health decline that should not be ignored.

Link:
Lack of Energy May Mean Lack of Testosterone – DrAxe.com

Breastfeeding: Hormones and Weaning – It Builds Character

July 17th, 2015 by inDZMTOPaaIJsLDD No comments »

When my 21-month old began the weaning process, I learned as much as I could about breast health and other related issues so I would know what to expect. I found a lot of information about the potential for depression and guilt associated with the loss of nursing as a bonding ritual. I am not one prone to depression and this has been a very gradual (and child-led) process for us. And, as I thought, Im experiencing nothing of this sort. What is completely surprising is my bodys hormone crash as my milk-producing system goes back to its natural state.

My initially confusing, very upsetting, but apparently common side effects include:

Why is this not common knowledge? A little warning would have been helpful. I suspect that this is a time in motherhood that were not as carefully monitored as during our pregnancy and initial postpartum period. Is it that after the baby is born, latches well, and our body parts directly involved with delivery heal, everyone assumes you go back to normal? I have chronic hip pain and diastasis recti (abdominal separation) both related to my pregnancy. I know Im not alone in this either but there isnt a lot of information out there. However, Ill save those for another post.

As for the weaning process, even the LeLeche League offers little or no detailed information about womens hormonal changes. After much searching online, I found most information limited to discussion boards where women shared their experiences. There is no readily available expert advice. Here are some important things I learned, gathered from the voices of other women who have weathered this change:

For the next few weeks, it seems Ill continue to weep at the slightest provocation and depend on the love and patience of my family. It seems to me there is a definite gap in womens healthcare that overlooks the importance of the postpartum bodys continued healing, sometimes years after delivery.

What has your experience with weaning been? Where have you found information youve needed?

Blissinmama lives on the north side of Chicago where shes the lucky parent of one adorable toddler. Shes also a yoga teacher and freelance editor. Other passions include cooking, reading, being outdoors, and travel. Her core parenting and life philosophy, and the mantra that keeps her grounded, is to live in the present and find the ability to take on those stressful moments from the perspective that all things are temporary. Email Blissinmama

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